Chris Kelly from NourishBalanceThrive recently interviewed me for his podcast.

Chris’ own most recent experiment with ketones fascinated me so I wanted to chat with him on if this kind of experiment can be reproduced in the general populace.  My biggest point is that we should exercise caution before regularly simultaneously raising blood glucose and ketones.

We also talk about why metabolic flexibility, not ketosis, should be the goal for most endurance athletes

The two most glaring problems had to do with impaired fat use and impaired carb use.

Enter Metabolic Flexibility.

  • [00:01:02] Keto Summit interview on Metabolic Flexibility.
  • [00:03:25] Complete Blueprint To Faster Results…Without Pain and Plateaus.
  • [00:06:14] Get the “Deadlift Re-alignment for Broken Meatheads.” for free.
  • [00:07:28] Online coaching.
  • [00:08:58]
  • [00:09:15] HRV for Successful Online Coaching with Dr. Mike T. Nelson.
  • [00:09:38] ithlete.
  • [00:12:29] Zoom video conference software.
  • [00:13:08] Instant Ketosis: 0.4 to 6.2mM in 30 Minutes.
  • [00:13:47] Dominic D’Agostino: Researcher and Athlete on the Benefits of a Ketogenic Diet.
    [00:15:34] Cox, Pete J., et al. “Nutritional ketosis alters fuel preference and thereby endurance performance in athletes.” Cell Metabolism 24.2 (2016): 256-268.
  • [00:16:57] Ketone esters for endurance performance.
  • [00:20:05] Ride time to exhaustion.
  • [00:21:04] Professor Kieran Clarke at Oxford University.
  • [00:22:27] Why You Should Skip Oxaloacetate Supplementation, Fueling for Your Activity and More!
  • [00:25:19] Brooks, George A., and Jacques Mercier. “Balance of carbohydrate and lipid utilization during exercise: the” crossover” ” Journal of applied physiology 76.6 (1994): 2253-2261.
  • [00:26:10] Ketone salts and C8 (caprylic) oil to “push the process”.
  • [00:28:05] Fasting and carbohydrate adaptation.
  • [00:28:18] Pyruvate dehydrogenase (PDH).
  • [00:29:39] Ketone supplements and appetite suppression.
  • [00:33:36] Jeff Rothschild.
  • [00:34:20] FATMAX and the hard transition.
  • [00:35:18] Peterson, Benjamin James. Repeated Sprint Ability: The Influence of Aerobic Capacity on Energy Pathway Response and Fatigue of Hockey Players. Diss. UNIVERSITY OF MINNESOTA, 2014.
  • [00:37:42] Reintroducing carbs.
  • [00:41:43] Sprints on wet tarmac (not recommended).
  • [00:46:22] Prioritizing strength in the offseason.
  • [00:48:40] Kiteboarding.
  • [00:49:55] Fortaleza.
  • [00:51:06] Mike’s email.

Rock on!
Dr Mike

Sciency References:

Problems with impaired fat use:

From  Nelson, Michael T., George R. Biltz, and Donald R. Dengel. “Repeatability of Respiratory Exchange Ratio Time Series Analysis.” The Journal of Strength & Conditioning Research 29.9 (2015): 2550-2558.

“Goedecke et al. (12) showed a very large interindividual variability in resting RER from 0.72 up to 0.93 that even persisted during exercise of increasing intensity. This corresponded to a relative rate of fat oxidation that ranged from 23 to 93%. This large interindividual variability in RER from 0.83 to 0.95 was also demonstrated by Helge et al. (16) during low-intensity steady-state exercise. This was quite similar to what we observed with a range of RER from 0.82 to 0.97.” (Nelson, MT, et al. 2015).

Problems with impaired carb use:

Research has shown that those are on a very low carb diet for prolonged periods of time demonstrate a reduced ability to fully use them during exercise (Burke, LM, et al.; Stellingwerf T. et al).